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Title: | Lipoproteomics: Methodologies and Analysis of Lipoprotein-Associated Proteins along with the Drug Intervention |
Authors: | Torres Romero, Julio César Lara Riegos, Julio César Estrella Parra, Edgar Antonio Fernández Sánchez, Verónica Arana Argáez, Víctor Ermilo Uc Colli, Sushally Peña Rico, Miguel Ángel Ramírez Camacho, Mario Alberto Ponce Regalado, María Dolores Alvarez Sánchez, María Elizbeth |
Keywords: | lipoproteins lipoproteomic proteomic high density lipoproteins (HDL) mass spectrometry (MS) |
Issue Date: | 14-Sep-2020 |
Citation: | Torres Romero JC, Lara Riegos JC, Estrella Parra EA, Fernández Sánchez V, Arana Argáez VE, Uc-Colli S, Peña RicoMA, Ramírez Camacho MA, Ponce Regalado MD and Alvarez Sánchez ME (September 14th 2020). Lipoproteomics: Methodologies and Analysis of Lipoprotein-Associated Proteins along with the Drug Intervention [Online First], IntechOpen, DOI: 10.5772/intechopen.93634. Available from: https://www.intechopen.com/online-first/lipoproteomics-methodologies-and-analysis-of-lipoprotein-associated-proteins-along-with-the-drug-int |
Abstract: | Abstract Lipoproteins are specialized particles involved in the transport and distribution of hydrophobic lipids, as cholesterol and triglycerides, throughout the body. The lipoproteins exhibit a basic spherical shape as complexes of lipids and proteins, and these latter are known as apolipoproteins. Initially, the proteins associated with lipoproteins were recognized as integral or peripheral proteins that only maintain the dynamics and metabolism of lipoproteins. However, there exist many studies on different lipoproteins evidencing that the quantity and type of apolipoproteins and lipoprotein-associated proteins are diverse and could be associated with different lipoprotein function outcomes. Here, we summarized recent processes in the determination of apolipoproteins and lipoprotein-associated proteins profiles through a proteomic approach, analyzing the major methods available and are used to achieve this. We also discuss the relevance of these lipoproteomic analyses on the human disease outcomes. |
URI: | https://www.intechopen.com/online-first/lipoproteomics-methodologies-and-analysis-of-lipoprotein-associated-proteins-along-with-the-drug-int http://repositorio.cualtos.udg.mx:8080/jspui/handle/123456789/1059 |
ISSN: | DOI: 10.5772/intechopen.93634 |
Appears in Collections: | 3210 Capítulos de libro y/o Reseñas |
Files in This Item:
File | Description | Size | Format | |
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Lipoproteomics.pdf | Documento | 269.22 kB | Adobe PDF | View/Open |
Enlace a_Lipoproteomics.htm | Enlace a publicación | 40.98 kB | HTML | View/Open |
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