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Title: | Biofunctionalization of Endolysins with Oligosacharides: Formulation of Therapeutic Agents to Combat Multi-Resistant Bacteria and Potential Strategies for Their Application |
Authors: | Camacho González, Carlos Eduardo Cardona Félix, César Salvador Zamora Gasga, Víctor Pérez Larios, Alejandro Sánchez Burgos, Jorge Alberto |
Keywords: | endolysins antibiotics aquaculture biofunctionalization |
Issue Date: | Jun-2022 |
Publisher: | MDPI |
Citation: | Camacho-González, C.E.; Cardona-Félix, C.S.; Zamora-Gasga, V.; Pérez-Larios, A.; Sánchez-Burgos, J.A. Biofunctionalization of Endolysins with Oligosacharides: Formulation of Therapeutic Agents to Combat Multi-Resistant Bacteria and Potential Strategies for Their Application. Polysaccharides 2022, 3, 306–325. https://doi.org/10.3390/ polysaccharides3020018 |
Series/Report no.: | Polysaccharides;2022, 3, 306–325 |
Abstract: | Abstract: In the aquaculture sector, the biofunctionalization of biomaterials is discussed using materials from algae and analyzed as a possible potential strategy to overcome the challenges that hinder the future development of the application of endolysins in this field. Derived from years of analysis, endolysins have recently been considered as potential alternative therapeutic antibacterial agents, due to their attributes and ability to combat multi-resistant bacterial cells when applied externally. On the other hand, although the aquaculture sector has been characterized by its high production rates, serious infectious diseases have led to significant economic losses that persist to this day. Although there are currently interesting data from studies under in vitro conditions on the application of endolysins in this sector, there is little or no information on in vivo studies. This lack of analysis can be attributed to the relatively low stability of endolysins in marine conditions and to the complex gastrointestinal conditions of the organisms. This review provides updated information regarding the application of endolysins against multi-resistant bacteria of clinical and nutritional interest, previously addressing their important characteristics (structure, properties and stability). In addition, regarding the aquaculture sector, the biofunctionalization of biomaterials is discussed using materials from algae and analyzed as a possible potential strategy to overcome the challenges that hinder the future development of the application of endolysins in this field. |
Description: | Artículo |
URI: | http://repositorio.cualtos.udg.mx:8080/jspui/handle/123456789/1313 |
ISSN: | 2673-4176 |
Appears in Collections: | 2414 Artículos |
Files in This Item:
File | Description | Size | Format | |
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Biofunctionalization of Endolysins with Oligosacharides.pdf | Documento | 2.24 MB | Adobe PDF | View/Open |
Enlace a_Biofunctionalization of Endolysins with Oligosacharides.htm | Enlace a publicación | 42.45 kB | HTML | View/Open |
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