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Title: | Drug delivery system of green synthesized Ti-Cu nanocomposite |
Authors: | Martín Camacho, Ubaldo de Jesús Torres Ramos, María Isabel Sánchez Burgos, Jorge Alberto Pérez Larios, Alejandro |
Keywords: | nanoparticles green synthesis drug release |
Issue Date: | Aug-2022 |
Publisher: | Elsevier - Science Direct |
Citation: | U.J. Martín-Camacho, M.I. Torres-Ramos, J.A. Sánchez-Burgos, A. Pérez-Larios. (2022). Drug delivery system of green synthesized Ti-Cu nanocomposite, Materials Letters, Volume 321, 2022, 132437, ISSN 0167-577X, https://doi.org/10.1016/j.matlet.2022.132437. (https://www.sciencedirect.com/science/article/pii/S0167577X2200790X) |
Series/Report no.: | Materials Letters;Vol. 321, 15 August 2022, 132437 |
Abstract: | Abstract: In this study, a drug delivery system was designed by the encapsulation of functionalized TiO2-Cu-Extract (TCE) nanoparticles obtained via green synthesis on a Poly(lactic-co-glycolic acid) (PLGA) matrix (TCE/PLGA). TCE nanoparticles showed improved optical absorption, band-gap energy, surface functional groups, and average nanoparticle size compared to pure TiO2 nanoparticles. The drug delivery system showed a controlled and sustained release for 24 h on simulated physiological conditions. β and n values of Weibull and Korsmeyer-Peppas models indicate that the release mechanism is a Fickian diffusion. Therefore, these results are promising for future research on the biomedical applications for TCE/PLGA drug delivery systems. |
Description: | Artículo |
URI: | http://repositorio.cualtos.udg.mx:8080/jspui/handle/123456789/1319 |
ISSN: | 0167-577X |
Appears in Collections: | 2414 Artículos |
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