Centro Universitario de los Altos
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http://repositorio.cualtos.udg.mx:8080/jspui/handle/123456789/132| Title: | Association Analysis Between -308G/A and -238G/A TNF-Alpha Gene Promoter Polymorphisms and Insulin Resistance in Mexican Women With Gestational Diabetes Mellitus. |
| Authors: | Guzmán Flores, Juan Manuel Escalante, Miguel García Zapién, Alejandra Guadalupe Cruz Quevedo, Edhit Guadalupe Muñoz Valle, José Francisco Moran Moguel, María Cristina Saldaña Cruz, Ana Miriam Flores Martínez, Silvia Esperanza |
| Keywords: | TNF-alpha insulin resistance DNA polymorphisms haplotypes gestational diabetes insulin resistance |
| Issue Date: | 2013 |
| Publisher: | Journal of Investigative Medicine & Volume 61, Number 2, February 2013;61: 265 Y 269 |
| Citation: | Guzma, J. M., Escalante, M., Cruz-quevedo, E. G., Mun, F., Moran-moguel, C., Saldan, A. M., & Flores-martı, S. E. (2013). Association Analysis Between Y 308G / A and Y 238G / A TNF-Alpha Gene Promoter Polymorphisms and Insulin Resistance in Mexican Women With Gestational Diabetes Mellitus. Journal of Investigative Medicine, 61(2), 265–269. doi:10.231/JIM.0b013e31827b98c9 |
| Abstract: | Gestational diabetes mellitus (GDM) is characterized by insulin resistance. It has been described that tumor necrosis factor α (TNF-α) plays a key role in the pathogenesis of insulin resistance; moreover, increased levels of this proinflammatory cytokine have been reported in women with GDM. Therefore, this study was aimed to assess the presence of associations between the -308G/A and -238G/A polymorphisms and specific haplotypes of the TNF-α gene promoter region and insulin resistance in Mexican women with GDM. |
| URI: | http://148.202.112.41:8080/jspui/handle/123456789/132 |
| ISSN: | 1708-8267 |
| Appears in Collections: | 3207 Artículos |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Association Analysis Between 308GA and 238GA final.pdf | Documento | 306.36 kB | Adobe PDF | View/Open |
| Enlace a_Association Analysis Between TNF-Alpha Gene Promoter Polymorphisms and Insulin Resistance in Mexican Women.htm | Enlace a publicación | 23.71 kB | HTML | View/Open |
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