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Title: | Neuro Immuno Endocrinology: A brief historic narrative |
Authors: | Ponce Regalado, María Dolores Pérez Sánchez, Gilberto Rojas Espinosa, Oscar Arce Paredes, Patricia Girón Pérez, Manuel Iván Pavón Romero, Lenin Becerril Villanueva, Luis Enrique |
Keywords: | neuroimmunoendocrinology neuroimmunomodulation neurophysiology and immunoregulation nueroendocrinology psychoimmunology psychoneuroimmunology |
Issue Date: | Jan-2022 |
Publisher: | Wiley Online Library |
Citation: | Ponce-Regalado MD, Pérez-Sánchez G, Rojas-Espinosa O, Arce-Paredes P, Girón-Peréz MI, Pavón-Romero L, Becerril-Villanueva E. Neuro Immuno Endocrinology: A brief historic narrative. J Leukoc Biol. 2022 Jan 31. doi: 10.1002/JLB.5MR1221-287R. Epub ahead of print. PMID: 35098580. |
Series/Report no.: | Journal of Leukocyte Biology;2022 Jan 31 |
Abstract: | Although no precise moment or unique event marks its birth, neuroimmunoendocrinology arguably shares a great deal of history with other medical and biologic disciplines. It originated from empirical observations and suppositions that failed to prevail upon the existing axioms. Despite the widespread resistance to embracing novel ideas, the seeming defeats inspired visionary researchers. Those pioneers managed to systematize the emerging knowledge and were able to contribute to science with real foundations. In consequence, new concepts and ideas arose in physiology, anatomy, endocrinology and early immunology. Together, they gave rise to a budding approach on the integration between the nervous, immune and endocrine systems. Then, neuroimmunoendocrinology emerged as a discipline integrating an intricate system with multidirectional functions and interactions that allow for responding to internal and external threats. Such response is mediated by cytokines, hormones and neurotransmitters, involved in different physiologic mechanisms of the organism homeostasis. Neuroimmunoendocrinology is no longer an area of scientific skepticism; on the contrary, it has cemented its position as a biomedical discipline worldwide for the past 70 years. Now, it offers a better understanding of pathologic processes. |
Description: | Artículo |
URI: | http://repositorio.cualtos.udg.mx:8080/jspui/handle/123456789/1350 |
ISSN: | 0741-5400 Print 1938-3673 Online 0741-5400 Linking |
Appears in Collections: | 3212 Artículos |
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