Please use this identifier to cite or link to this item: http://repositorio.cualtos.udg.mx:8080/jspui/handle/123456789/1439
Title: Extraction of Acetogenins Using Thermosonication-Assisted Extraction from Annona muricata Seeds and Their Antifungal Activity
Authors: López Romero, Brandon Alexis
Luna Bárcenas, Gabriel
García Magaña, María de Lourdes
Anaya Esparza, Luis Miguel
Zepeda Vallejo, Luis Gerardo
López García, Ulises Miguel
Ortiz Basurto, Rosa Isela
Aguilar Hernández, Gabriela
Pérez Larios, Alejandro
Montalvo González, Efigenia
Keywords: A. muricata seeds
acetogenins
thermosonication-assisted extraction
Issue Date: Sep-2022
Publisher: MDPI
Citation: López-Romero, B.A.; Luna-Bárcenas, G.; García-Magaña, M.d.L.; Anaya-Esparza, L.M.; Zepeda-Vallejo, L.G.; López-García, U.M.; Ortiz-Basurto, R.I.; Aguilar-Hernández, G.; Pérez-Larios, A.; Montalvo-González, E. Extraction of Acetogenins Using Thermosonication-Assisted Extraction from Annona muricata Seeds and Their Antifungal Activity. Molecules 2022, 27, 6045. https:// doi.org/10.3390/molecules27186045
Series/Report no.: Molecules;2022, 27(18), 6045
Abstract: The objective of this work was to find the optimal conditions by thermosonication-assisted extraction (TSAE) of the total acetogenin content (TAC) and yield from A. muricata seeds, assessing the effect of the temperature (40, 50, and 60 ◦C), sonication amplitude (80, 90, and 100%), and pulse-cycle (0.5, 0.7, and 1 s). In addition, optimal TSAE conditions of acetogenins (ACGs) were compared with extraction by ultrasound at 25 ◦C and the soxhlet method measuring TAC and antioxidant capacity. Moreover, solubility and identification of isolated ACGs were performed. Furthermore, the antifungal activity of ACGs crude extract and isolated ACGs was evaluated. Optimal TSAE conditions to extract the highest TAC (35.89 mg/g) and yield (3.6%) were 50 ◦C, 100% amplitude, and 0.5 s pulse-cycle. TSAE was 2.17-fold and 15.60-fold more effective than ultrasound at 25 ◦C and the Soxhlet method to extract ACGs with antioxidant capacity. Isolated ACGs were mostly soluble in acetone and methanol. Seven ACGs were identified, and pseudoannonacin was the most abundant. The inhibition of Candida albicans, Candida krusei, and Candida tropicalis was higher from isolated ACGs than crude extract. TSAE was effective to increase the yield in the ACGs extraction from A. muricata seeds and these ACGs have important antifungal activity.
Description: Artículo
URI: http://repositorio.cualtos.udg.mx:8080/jspui/handle/123456789/1439
ISSN: 1420-3049
https:// doi.org/10.3390/molecules27186045
Appears in Collections:2414 Artículos

Files in This Item:
File Description SizeFormat 
Extraction of Acetogenins Using Thermosonication.pdfDocumento2.54 MBAdobe PDFView/Open
Enlace a_Extraction of Acetogenins Using Thermosonication.htmEnlace a publicación43.14 kBHTMLView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.