Please use this identifier to cite or link to this item: http://repositorio.cualtos.udg.mx:8080/jspui/handle/123456789/1479
Title: Local Tramadol Improves the Anesthetic Success in Patients with Symptomatic Irreversible Pulpitis: A Meta-Analysis
Authors: Gómez Sánchez, Eduardo
Franco de la Torre, Lorenzo
Bologna Molina, Ronell Eduardo
Molina Frechero, Nelly
Serafín Higuera, Nicolás Addiel
Hernández Gómez, Adriana
Alonso Castro, Ángel Josabad
Sat Muñoz, Daniel
Isiordia Espinoza, Mario Alberto
Keywords: tramadol
symptomatic irreversible pulpitis
anesthesia success rate
pain control
adverse effects
Issue Date: Oct-2022
Publisher: MDPI. International Journal of Environmental Research and Public Health
Citation: Gómez-Sánchez, E.; Franco-de la Torre, L.; Bologna-Molina, R.E.; Molina-Frechero, N.; Serafín-Higuera, N.A.; Hernández-Gómez, A.; Alonso-Castro, Á.J.; Sat-Muñoz, D.; Isiordia-Espinoza, M.A. Local Tramadol Improves the Anesthetic Success in Patients with Symptomatic Irreversible Pulpitis: A Meta-Analysis.
Series/Report no.: Healthcare;2022, 10 (10), 1867.
Abstract: Abstract Symptomatic irreversible pulpitis is a painful clinical condition with a broad inflammatory component. Dental anesthesia in these patients is affected by the inflammatory process, reporting a high incidence of anesthesia failure. The aim of this systematic review and meta-analytical evaluation was to determine the effect of pre-treatment with tramadol in patients with symptomatic irreversible pulpitis, as well as for pain control and adverse effects. This study was registered in PROSPERO (ID: CRD42021279262). PubMed was consulted to identify clinical investigations comparing tramadol and placebo/local anesthetics in patients with symptomatic irreversible pulpitis. Data about the anesthesia, pain control, and adverse effects were extracted. Both the anesthetic success index and the adverse effects of local tramadol and placebo were compared with the Mantel–Haenszel test and odds ratio. Data analysis showed that the local administration of tramadol increased the anesthetic success rate when compared to placebo in patients with symptomatic irreversible pulpitis (n = 228; I2 = 0; OR = 2.2; 95% CIs: 1.30 to 3.79; p < 0.004). However, local administration of tramadol increased the risk of adverse effects when compared to placebo/local anesthetics (n = 288; I2 = 0; OR = 7.72; 95% CIs: 1.37 to 43.46; p < 0.02). In conclusion, this study shows that the local administration of tramadol increases the anesthetic success index when compared to placebo in patients with symptomatic irreversible pulpitis.
Description: Artículo
URI: http://repositorio.cualtos.udg.mx:8080/jspui/handle/123456789/1479
ISSN: 2227-9032
https://doi.org/10.3390/ healthcare10101867
Appears in Collections:3303 Artículos



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