Please use this identifier to cite or link to this item: http://repositorio.cualtos.udg.mx:8080/jspui/handle/123456789/1709
Title: Association between fluoride intake from drinking water and severity of dental fluorosis in Northern and Western Mexico: systematic review and meta-analysis
Authors: Gamarra, José
Álvarez Ordaz, David
Molina Frechero, Nelly
Sánchez Pérez, Leonor
Pierdant Rodriguez, Alberto
Isiordia Espinoza, Mario Alberto
Espinosa Cristóbal, León Francisco
Gómez Palacio Gastelum, Marcelo
González González, Rogelio
Salas Pacheco, José
Bologna Molina, Ronell
Keywords: Fluoride in drinking water
Dental fluorosis
Northern and western Mexico
Issue Date: Jun-2024
Publisher: Springer Nature
Citation: Gamarra, J., Álvarez-Ordaz, D., Molina-Frechero, N. et al. Association between fluoride intake from drinking water and severity of dental fluorosis in Northern and Western Mexico: systematic review and meta-analysis. BMC Oral Health 24, 708 (2024). https://doi.org/10.1186/s12903-024-04472-7
Series/Report no.: BMC Oral Health;24, 708 (2024)
Abstract: Background Dental fluorosis (DF) is caused by excessive exposure to fluoride during odontogenesis and leads to various changes in the development of tooth enamel. Some regions in Mexico are considered endemic fluorosis zones due to the high fluoride content in drinking water. The objective of this study was to perform a systematic review and meta-analysis to identify the association between the concentration of fluoride in drinking water and the severity of dental fluorosis in northern and western Mexico. Methods This protocol was registered in the PROSPERO database (ID: CRD42023401519). The search for information was carried out in the PubMed/Medline, Scopus, SpringerLink, and Google Scholar databases between January 2015 and October 2023. The overall relative risk was calculated using the inverse of variance approach with the random effects method. The RoB 2.0 tool was used to construct risk plots. Results Eleven articles were analyzed qualitatively, and most of the included studies presented at least one level of DF severity; six articles were analyzed quantitatively, dividing them into two regions. In North region it was observed a higher prevalence of severe TF cases, corresponding to ≥ TF 5 category (4.78) [3.55, 6.42]. In the West region, most of the included studies presented a higher prevalence of less severe cases, corresponding to ≤ TF 4, in comparison with the North region (0.01) [0.00, 0.52], interpreted as a protective effect. Conclusion The concentrations of fluorides in drinking water are reportedly high in these regions and are directly related to the severity of dental fluorosis experienced by the inhabitants. In the Northern region exists a major concentration of fluoride in drinking water compared with the Western region as well as a prevalence of higher severity cases of dental fluorosis.
Description: Artículo
URI: http://repositorio.cualtos.udg.mx:8080/jspui/handle/123456789/1709
ISSN: 1472-6831
Appears in Collections:3209 Artículos



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