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Title: | Onco-Ontogeny of Squamous Cell Cancer of the First Pharyngeal Arch Derivatives |
Authors: | Sat Muñoz, Daniel Balderas Peña, Luz María Adriana Gómez Sánchez, Eduardo Martínez Herrera, Brenda Eugenia Trujillo Hernández, Benjamín Quiroga Morales, Luis Aarón Salazar Páramo, Mario Dávalos Rodríguez, Ingrid Patricia Nuño Guzmán, Carlos M. Velázquez Flores, Martha Cecilia Ochoa Plascencia, Miguel Ricardo Muciño Hernández, María Ivette Isiordia Espinoza, Mario Alberto Mireles Ramírez, Mario Alberto Hernández Salazar, Eduardo |
Keywords: | onco-ontogeny head and neck squamous cell carcinoma notch HOX BMP |
Issue Date: | Sep-2024 |
Publisher: | MDPI |
Citation: | Sat-Muñoz, D.; Balderas- Peña, L.-M.-A.; Gómez-Sánchez, E.; Martínez-Herrera, B.-E.; Trujillo- Hernández, B.; Quiroga-Morales, L.-A.; Salazar-Páramo, M.; Dávalos- Rodríguez, I.-P.; Nuño-Guzmán, C.M.; Velázquez-Flores, M.-C.; et al. Onco-Ontogeny of Squamous Cell Cancer of the First Pharyngeal Arch Derivatives. Int. J. Mol. Sci. 2024, 25, 9979. https://doi.org/10.3390/ ijms25189979 |
Series/Report no.: | Int. J. Mol. Sci.;25(18), 9979 |
Abstract: | Head and neck squamous cell carcinoma (H&NSCC) is an anatomic, biological, and genetic complex disease. It involves more than 1000 genes implied in its oncogenesis; for this review, we limit our search and description to the genes implied in the onco-ontogeny of the derivates from the first pharyngeal arch during embryo development. They can be grouped as transcription factors and signaling molecules (that act as growth factors that bind to receptors). Finally, we propose the term embryo-oncogenesis to refer to the activation, reactivation, and use of the genes involved in the embryo’s development during the oncogenesis or malignant tumor invasion and metastasis events as part of an onco-ontogenic inverse process. |
Description: | Artículo |
URI: | http://repositorio.cualtos.udg.mx:8080/jspui/handle/123456789/1712 |
ISSN: | 1422-0067 |
Appears in Collections: | 3209 Artículos |
Files in This Item:
File | Description | Size | Format | |
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Onco-Ontogeny of Squamous Cell Cancer of the First Pharyngeal Arch Derivates.pdf | Documento | 795.35 kB | Adobe PDF | View/Open |
Enlace a_Onco-Ontogeny of Squamous Cell Cancer .htm | Enlace a publicación | 64.7 kB | HTML | View/Open |
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