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DC Field | Value | Language |
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dc.contributor.author | González García, Juan Ramón | - |
dc.contributor.author | Bohlander, Stefan K. | - |
dc.contributor.author | Gutiérrez Angulo, Melva | - |
dc.contributor.author | Esparza Flores, María Amparo | - |
dc.contributor.author | Picos Cárdenas, Verónica Judith | - |
dc.contributor.author | Meza Espinoza, Juan Pablo | - |
dc.contributor.author | Ayala Madrigal, María de la Luz | - |
dc.contributor.author | Rivera, Horacio | - |
dc.date.accessioned | 2015-08-17T14:33:42Z | - |
dc.date.available | 2015-08-17T14:33:42Z | - |
dc.date.issued | 2004 | - |
dc.identifier.issn | 0165-4608 | - |
dc.identifier.other | doi:10.1016/j.cancergencyto.2003.10.014 | - |
dc.identifier.uri | http://repositorio.cualtos.udg.mx:8080/jspui/handle/123456789/375 | - |
dc.description.abstract | Recurring chromosome translocations, which are found in leukemia, can result in the inappropriate expression of oncogenes or in the formation of chimeric genes that code for structurally and functionally abnormal proteins. The chromosomal t(1;9)(q23.3~q25;q34) was found in a patient with biphenotypic leukemia. Fluorescence in situ hybridization (FISH) analysis revealed that the break on chromosome 9 occurred in the ABL1 gene. The breakpoint on chromosome 1 occurred distal to the PBX1 gene at 1q23.3, as shown by FISH using BAC RP11-503N16 and RP11-403P14, which flank the PBX1 locus; hence, the ABL1 gene can be fused with another gene distal to PBX1 gene. | es, en |
dc.description.sponsorship | Laboratorio de Citogenética, Centro de Investigación Biomédica de Occidente, Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social (CIBO-IMSS), Sierra Mojada #800, Colonia Independencia, Guadalajara, Jalisco AP 1-3838, México Medizinische Klinik und Poliklinik III, Klinikum Grosshadern, Raum 003, Clinical Cooperative Group ‘Leukemia’, GSF, Marchioninistrasse 25, 81377 München, Germany Doctorado en Genética Humana, Universidad de Guadalajara, Guadalajara, México Departamento de Hematología, Hospital de Pediatría, Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social (CMNO-IMSS), Sierra Mojada #800, Colonia Independencia, Guadalajara, Jalisco AP 1-3838, México | es, en |
dc.language.iso | en | es, en |
dc.publisher | Elsevier Inc. | es, en |
dc.relation.ispartofseries | Cancer Genetics and Cytogenetics;152 (2004) 81–83 | - |
dc.title | A t(1;9)(q23.3~q25;q34) affecting the ABL1 gene in a biphenotypic leukemia. | es, en |
dc.title.alternative | Short communication | es, en |
dc.type | Article | es, en |
Appears in Collections: | 2409 Artículos |
Files in This Item:
File | Description | Size | Format | |
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Enlace a_A t(1;9).htm | Enlace a publicación | 24.06 kB | HTML | View/Open |
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